| Hydrophilic jelly capsule (500 units) containing microemulsion consisting of frankincense oil (Boswellia serrata), quercetin (Crocus sativus), and nanoparticles of iron pollutants coated with fulvic acid to prevent Alzheimer's disease |
| Paper ID : 1323-NICAME1402 |
| Authors: |
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Parmida Barikani *, Dina Yaghobloo Farzanegan1 |
| Abstract: |
| Alzheimer's disease is the most common type of dementia and it is actually a type of neurodegenerative disease whose prominent symptoms are the formation of amyloid beta protein aggregates followed by the phosphorylation of tau fibrils and the formation of interwoven nerve fibrils. veins and other brain cells and it severely affects the personal and social life of the patient. Despite extensive efforts in the field of prevention or treatment of Alzheimer's disease, there is still no definite cure for this disease. Among the types of drugs, nanomedicines with their small size are able to cross the blood-brain barrier and can enter neurons. Drugs effective in the treatment of Alzheimer's based on compounds alone are not able to cross the blood-brain barrier or are insoluble in water and will not be able to pass through the aqueous environment of the human body. As a result, in order to optimize the effect of anti-Alzheimer herbal compounds, the presence of drug carriers based on nanostructures is essential. In this invention, for the first time, iron oxide nanoparticles are coated with fulvic acid, which is a polyphenol with anti-inflammatory properties, anti-amyloid-beta and tau accumulations, as well as neuron-protective properties. |
| Keywords: |
| Boswell serrate , Crocus sativa , Sesquiterpene , ... |
| Status : Paper Accepted |
